![Inhibition of histone acetyltransferase function radiosensitizes CREBBP/ EP300 mutants via repression of homologous recombination, potentially targeting a gain of function | Nature Communications Inhibition of histone acetyltransferase function radiosensitizes CREBBP/ EP300 mutants via repression of homologous recombination, potentially targeting a gain of function | Nature Communications](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-021-26570-8/MediaObjects/41467_2021_26570_Fig10_HTML.png)
Inhibition of histone acetyltransferase function radiosensitizes CREBBP/ EP300 mutants via repression of homologous recombination, potentially targeting a gain of function | Nature Communications
![Schematic presentation of the EP300 protein illustrating its functional... | Download Scientific Diagram Schematic presentation of the EP300 protein illustrating its functional... | Download Scientific Diagram](https://www.researchgate.net/publication/327144102/figure/fig1/AS:961365086846976@1606218706448/Schematic-presentation-of-the-EP300-protein-illustrating-its-functional-domains-with-the.gif)
Schematic presentation of the EP300 protein illustrating its functional... | Download Scientific Diagram
![Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma - ScienceDirect Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1074761319303322-fx1.jpg)
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma - ScienceDirect
![Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1: Cell Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1: Cell](https://www.cell.com/cms/attachment/cd06e5b4-87ca-4ad1-a923-bfa72ba6911c/fx1_lrg.jpg)
Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1: Cell
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Cancers | Free Full-Text | The Role of CREBBP/EP300 and Its Therapeutic Implications in Hematological Malignancies
![Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation - ScienceDirect Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124719303158-fx1.jpg)
Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation - ScienceDirect
![CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation | Epigenetics & Chromatin | Full Text CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation | Epigenetics & Chromatin | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13072-018-0197-x/MediaObjects/13072_2018_197_Fig7_HTML.png)
CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation | Epigenetics & Chromatin | Full Text
![Cancers | Free Full-Text | The Role of CREBBP/EP300 and Its Therapeutic Implications in Hematological Malignancies Cancers | Free Full-Text | The Role of CREBBP/EP300 and Its Therapeutic Implications in Hematological Malignancies](https://pub.mdpi-res.com/cancers/cancers-15-01219/article_deploy/html/images/cancers-15-01219-g002.png?1676988320)
Cancers | Free Full-Text | The Role of CREBBP/EP300 and Its Therapeutic Implications in Hematological Malignancies
![CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation | Epigenetics & Chromatin | Full Text CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation | Epigenetics & Chromatin | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13072-018-0197-x/MediaObjects/13072_2018_197_Fig2_HTML.png)
CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation | Epigenetics & Chromatin | Full Text
![STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease | Clinical Epigenetics | Full Text STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease | Clinical Epigenetics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13148-021-01101-w/MediaObjects/13148_2021_1101_Figa_HTML.png)
STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease | Clinical Epigenetics | Full Text
![Frontiers | Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data Frontiers | Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data](https://www.frontiersin.org/files/Articles/729474/fphar-12-729474-HTML/image_m/fphar-12-729474-g003.jpg)
Frontiers | Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data
![Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53 | PNAS Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53 | PNAS](https://www.pnas.org/cms/10.1073/pnas.0702010104/asset/58bbef58-33af-42a4-8a0a-bd39dd807b91/assets/graphic/zpq0160760030001.jpeg)
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53 | PNAS
![Cancers | Free Full-Text | Pharmacological Inhibition of CBP/p300 Blocks Estrogen Receptor Alpha (ERα) Function through Suppressing Enhancer H3K27 Acetylation in Luminal Breast Cancer Cancers | Free Full-Text | Pharmacological Inhibition of CBP/p300 Blocks Estrogen Receptor Alpha (ERα) Function through Suppressing Enhancer H3K27 Acetylation in Luminal Breast Cancer](https://pub.mdpi-res.com/cancers/cancers-13-02799/article_deploy/html/images/cancers-13-02799-ag.png?1622800137)